FREE RADICAL PRODUCTION INDUCED BY NITROIMIDAZOLE COMPOUNDS LEAD TO CELL DEATH IN LEISHMANIA INFANTUM AMASTIGOTES

Free Radical Production Induced by Nitroimidazole Compounds Lead to Cell Death in Leishmania infantum Amastigotes

Leishmania infantum is the vector-borne trypanosomatid parasite causing visceral leishmaniasis in the Mediterranean basin.This neglected tropical disease is treated with a limited number of obsolete drugs that are not exempt from read more adverse effects and whose overuse has promoted the emergence of resistant pathogens.In the search for novel an

read more

Potential role of polycyclic aromatic hydrocarbons as mediators of cardiovascular effects from combustion particles

Abstract Air pollution is the most important environmental risk factor for disease and premature death, and exposure to combustion particles from vehicles is a major contributor.Human epidemiological studies combined with experimental studies strongly suggest that exposure to combustion particles may enhance the risk of cardiovascular disease (CVD)

read more